James Chester, Kortney Hause and Jonathan Kodjia will all miss the Bournemouth clash this weekend.
Chester (hamstring) and Hause (ankle) have issues picked up in pre-season.
However, Kodjia (ankle) got injured shortly after coming on in the Premier League opener with Spurs and now misses the Cherries match at the weekend.
Head Coach Dean Smith said: “James is still missing. Kortney is still missing.
“Kortney picked up an ankle injury in Leipzig.
“Jon got injured early in the Tottenham match but managed to see the game out. He’s got a high ankle sprain so he’ll be about 10-12 days out.”